Christina Applegate says on her podcast that she was misdiagnosed with multiple sclerosis
Christina Applegate said on her MeSsy podcast that her doctor recently told her she did not have multiple sclerosis. CBS News reported her comments Tuesday evening. NBC News reported earlier Tuesday that she said she was misdiagnosed with the neurological and autoimmune disorder. The Hill, ABC News and Fox News also carried the story. The reports did not name the condition she now has.
Multiple sclerosis is a chronic disease of the central nervous system and its symptoms overlap with other conditions, so diagnosis often requires imaging and repeated testing. A public figure's disclosure draws attention to how misdiagnosis can happen.
If you have symptoms that doctors attribute to MS or another neurological illness, a second opinion from a specialist is a standard option. Her case is one person's experience and not a trend.
Applegate's account, as reported, emphasizes the shock of learning years later that a diagnosis was wrong.
Patient advocates for MS note that the disease can be hard to confirm and that diagnosis is made by specialists using established criteria; the reports did not include such commentary directly.
Confirmed by NBC News and CBS News: her statement on the podcast. Not confirmed: her new diagnosis or the details of her medical history. Watch for further comments from Applegate.
DailyDrop U.S. No. 17 · October 21, 2026